Annual report [Section 13 and 15(d), not S-K Item 405]

Cover

v3.25.1
Cover - USD ($)
12 Months Ended
Dec. 31, 2024
Mar. 31, 2025
Jun. 30, 2024
Document Information [Line Items]      
Document Type 10-K    
Document Annual Report true    
Document Transition Report false    
Document Financial Statement Error Correction [Flag] false    
Entity Interactive Data Current Yes    
ICFR Auditor Attestation Flag false    
Amendment Flag false    
Document Period End Date Dec. 31, 2024    
Document Fiscal Year Focus 2024    
Document Fiscal Period Focus FY    
Documents Incorporated by Reference [Text Block]

Portions of the registrant’s definitive proxy statement relating to its 2025 annual meeting of shareholders (the “2025 Proxy Statement”) are incorporated by reference into Part III of this Annual Report on Form 10-K where indicated. The 2025 Proxy Statement will be filed with the U.S. Securities and Exchange Commission within 120 days after the end of the fiscal year to which this report relates. 

   
Entity Information [Line Items]      
Entity Registrant Name 180 LIFE SCIENCES CORP.    
Entity Central Index Key 0001690080    
Entity File Number 001-38105    
Entity Tax Identification Number 90-1890354    
Entity Incorporation, State or Country Code DE    
Current Fiscal Year End Date --12-31    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Shell Company false    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
Entity Public Float     $ 1,548,662
Entity Contact Personnel [Line Items]      
Entity Address, Address Line One 3000 El Camino Real, Bldg. 4    
Entity Address, Address Line Two Suite 200    
Entity Address, City or Town Palo Alto    
Entity Address, State or Province CA    
Entity Address, Postal Zip Code 94306    
Entity Phone Fax Numbers [Line Items]      
City Area Code (650)    
Local Phone Number 285-2387    
Entity Listings [Line Items]      
Entity Common Stock, Shares Outstanding   5,185,780  
Common Stock, par value $0.0001 per share      
Entity Listings [Line Items]      
Title of 12(b) Security Common Stock, par value $0.0001 per share    
Trading Symbol ATNF    
Security Exchange Name NASDAQ    
Warrants to purchase shares of Common Stock      
Entity Listings [Line Items]      
Title of 12(b) Security Warrants to purchase shares of Common Stock    
Trading Symbol ATNFW    
Security Exchange Name NASDAQ