Annual report pursuant to Section 13 and 15(d)

Document And Entity Information

Document And Entity Information - USD ($)
12 Months Ended
Dec. 31, 2022
Mar. 31, 2023
Document Information Line Items    
Entity Registrant Name 180 LIFE SCIENCES CORP.  
Trading Symbol ATNF  
Document Type 10-K  
Current Fiscal Year End Date --12-31  
Entity Common Stock, Shares Outstanding   3,746,906
Entity Public Float $ 25,377,272  
Amendment Flag false  
Entity Central Index Key 0001690080  
Entity Current Reporting Status Yes  
Entity Voluntary Filers No  
Entity Filer Category Non-accelerated Filer  
Entity Well-known Seasoned Issuer No  
Document Period End Date Dec. 31, 2022  
Document Fiscal Year Focus 2022  
Document Fiscal Period Focus FY  
Entity Small Business true  
Entity Emerging Growth Company false  
Entity Shell Company false  
ICFR Auditor Attestation Flag false  
Document Annual Report true  
Document Transition Report false  
Entity File Number 001-38105  
Entity Incorporation, State or Country Code DE  
Entity Tax Identification Number 90-1890354  
Entity Address, Address Line One 3000 El Camino Real, Bldg. 4  
Entity Address, Address Line Two Suite 200  
Entity Address, City or Town Palo Alto  
Entity Address, State or Province CA  
Entity Address, Postal Zip Code 94306  
City Area Code (650)  
Local Phone Number 507-0669  
Title of 12(b) Security Common Stock, par value $0.0001 per share  
Security Exchange Name NASDAQ  
Entity Interactive Data Current Yes  
Auditor Firm ID 688  
Auditor Name Marcum, LLP  
Auditor Location San Francisco, CA