Annual report [Section 13 and 15(d), not S-K Item 405]

Cover

v3.25.1
Cover - USD ($)
12 Months Ended
Dec. 31, 2024
Mar. 31, 2025
Jun. 30, 2024
Document Information [Line Items]      
Document Type 10-K/A    
Document Annual Report true    
Document Transition Report false    
Document Financial Statement Error Correction [Flag] false    
Entity Interactive Data Current Yes    
ICFR Auditor Attestation Flag false    
Amendment Flag true    
Amendment Description On March 31, 2025, 180 Life Sciences Corp. (“180 Life,” the “Company,” “we,” “us,” or “our”) filed its Annual Report on Form 10-K for the fiscal year ended December 31, 2024 (the “Original Form 10-K”) with the U.S. Securities and Exchange Commission (the “SEC”). The Original Form 10-K omitted certain disclosures under Part III, Items 10, 11, 12, 13 and 14 of Form 10-K in reliance on General Instruction G(3) to Form 10-K, which provides that such information may be either incorporated by reference from the registrant’s definitive proxy statement or included in an amendment to Form 10-K, in either case filed with the SEC not later than 120 days after the end of the fiscal year. Subsequently, on April 25, 2025, the Company filed an Amendment No. 1 to Annual Report on Form 10-K with the SEC to include such omitted information (“Amendment No. 1”).Amendment No. 1 failed to include certain required XBRL tagging and this Amendment No. 2 to Annual Report on Form 10-K is being filed solely to include such XBRL tagging under Item 10. Directors, Executive Officers and Corporate Governance.As such, this Amendment No. 2: ●restates Part III, Item 10 (Directors, Executive Officers and Corporate Governance), 11 (Executive Compensation), of Amendment No. 1 to include the required XBRL tagging; and ●files new certifications of our principal executive officer and principal financial officer as exhibits to this Amendment under Item 15 of Part IV hereof, pursuant to Rule 12b-15 under the Securities Exchange Act of 1934, as amended (the “Exchange Act”). This Amendment No. 2 does not otherwise change or update any of the disclosures set forth in the Original Form 10-K, as amended by Amendment No. 1, and, except as expressly stated herein, does not reflect events occurring after the filing of the Original Form 10-K.Unless the context requires otherwise, references to the “Company,” “we,” “us,” “our,” “180 Life”, “180LS” and “180 Life Sciences Corp.” refer specifically to 180 Life Sciences Corp. and its consolidated subsidiaries. References to “KBL” refer to the Company prior to our November 6, 2020 Business Combination.In addition, unless the context otherwise requires and for the purposes of this Report only: ●“180” refers to 180 Life Corp. (f/k/a 180 Life Sciences Corp.), our wholly-owned subsidiary. “Business Combination” means that certain business combination which closed on November 6, 2020, between KBL, KBL Merger Sub, Inc. (“Merger Sub”), 180, Katexco Pharmaceuticals Corp. (“Katexco”), CannBioRex Pharmaceuticals Corp. (“CBR Pharma”), 180 Therapeutics L.P. (“180 LP” and together with Katexco and CBR Pharma, the “180 Subsidiaries” and, together with 180 Life Sciences Corp., the “180 Parties”), and Lawrence Pemble, in his capacity as representative of the stockholders of the 180 Parties, whereby KBL acquired the 180 Subsidiaries. ●“CAD” refers to Canadian dollars; ●“Exchange Act” refers to the Securities Exchange Act of 1934, as amended; ●“£” or “GBP” refers to British pounds sterling; ●“SEC” or the “Commission” refers to the United States Securities and Exchange Commission; and ●“Securities Act” refers to the Securities Act of 1933, as amended.    
Document Period End Date Dec. 31, 2024    
Document Fiscal Year Focus 2024    
Document Fiscal Period Focus FY    
Documents Incorporated by Reference [Text Block] None    
Entity Information [Line Items]      
Entity Registrant Name 180 LIFE SCIENCES CORP.    
Entity Central Index Key 0001690080    
Entity File Number 001-38105    
Entity Tax Identification Number 90-1890354    
Entity Incorporation, State or Country Code DE    
Current Fiscal Year End Date --12-31    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Shell Company false    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
Entity Public Float     $ 1,548,662
Entity Contact Personnel [Line Items]      
Entity Address, Address Line One 3000 El Camino Real, Bldg. 4    
Entity Address, Address Line Two Suite 200    
Entity Address, City or Town Palo Alto    
Entity Address, State or Province CA    
Entity Address, Postal Zip Code 94306    
Entity Phone Fax Numbers [Line Items]      
City Area Code (650)    
Local Phone Number 507-0669    
Entity Listings [Line Items]      
Entity Common Stock, Shares Outstanding   5,185,780  
Common Stock, par value $0.0001 per share      
Entity Listings [Line Items]      
Title of 12(b) Security Common Stock, par value $0.0001 per share    
Trading Symbol ATNF    
Security Exchange Name NASDAQ    
Warrants to purchase shares of Common Stock      
Entity Listings [Line Items]      
Title of 12(b) Security Warrants to purchase shares of Common Stock    
Trading Symbol ATNFW    
Security Exchange Name NASDAQ